Lily Gladstone (born August 2, 1986) is an American actress. Her father is of Piegan Blackfeet and Nez Perce heritage, and her mother of European heritage. She was raised on a Blackfeet reservation in Montana until she was ten. She made her film debut in Jimmy P: Psychotherapy of a Plains Indian (2012), and collaborated with filmmaker Kelly Reichardt in the independent films Certain Women (2016) and First Cow (2019). They also appeared in episodes of HBO's Room 104 (2017–2020), Showtime's Billions (2016–2023), and FX's Reservation Dogs (2021–2023).

Gladstone earned critical acclaim for playing Mollie Kyle in Martin Scorsese's crime drama film Killers of the Flower Moon (2023), receiving several accolades. They became the first Native American to win the Golden Globe and SAG Award for Best Actress and the first to receive a nomination for the Academy Award for Best Actress. Gladstone earned her first Primetime Emmy nomination for Best Supporting Actress for her role as Cam Bentland in the miniseries Under the Bridge (2024).

In 2023, Gladstone said that she is comfortable with both she and they pronouns. They explained that their pronouns are partly a way of decolonizing gender for themself, as there are no gendered pronouns in the Blackfeet language nor in most Indigenous languages.